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DeCS
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Descriptor English:
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APOBEC-3G Deaminase
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Descriptor Spanish:
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Desaminasa APOBEC-3G
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Descriptor Portuguese:
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Desaminase APOBEC-3G
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Synonyms English:
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APOBEC 3G Deaminase
APOBEC 3G Protein
APOBEC 3G dC dU Editing Enzyme
APOBEC Related Cytidine Deaminase
APOBEC Related Protein
APOBEC-3G Protein
APOBEC-3G dC-dU Editing Enzyme
APOBEC-Related Cytidine Deaminase
APOBEC-Related Protein
APOBEC3G Deaminase
APOBEC3G Protein
CEM15 Protein
Cytidine Deaminase, APOBEC-Related
Deaminase, APOBEC-3G
Deaminase, APOBEC3G
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Tree Number:
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D08.811.277.151.486.250.500.750
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Definition English:
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An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56472
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Unique Identifier:
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D000071480
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Occurrence in VHL:
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Similar:
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DeCS
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